Ageing Skin Routine: How to help Replump and Strengthen Your Skin

If your skin looks less plump or has lost its glow, you're not alone. At the heart of L'Oréal Paris' latest innovation is a complementary duo: Hyaluronic Acid (HA) and PDRN+, two ingredient inspired by aesthetic medicine that deliver a skin transformation you can see and feel. Here's everything you need to know about building an anti-ageing routine that truly works.

Why Does Skin Age?

Over time, skin slows its renewal and produces less collagen, elastin, and hyaluronic acid. Research shows that HA content in the epidermis can drop by half between ages 19 and 60, and nearly disappear by age 70 — directly causing dryness, fine lines, and loss of volume. External aggressors — UV radiation, pollution, glycation — accelerate this process by breaking down the extracellular matrix and triggering oxidative stress.

At the cellular level, fibroblasts become less active with age. Studies have shown that papillary dermal fibroblasts are particularly affected, losing their ability to support skin architecture. Meanwhile, UV exposure combined with glycation promotes the formation of Advanced Glycation End Products (AGEs) and creates a favorable environment for elastosis — the degradation of elastic fibers. Research on skin diversity also confirms that ageing manifests differently across ethnicities, affecting the order and prominence of wrinkles, sagging, and pigmentation changes.

Signs of Ageing Skin

While ageing looks different depending on skin type and ethnicity, there are some universal signs that appear across all skin tones. Here's what to watch for:

• Loss of plumpness: Skin feels thinner, especially around cheeks and under-eyes.
• Fine lines and wrinkles: First around the eyes, then deepening over time.
• Dull complexion: Reduced cell turnover leads to lost radiance.
• Reduced elasticity: Skin takes longer to bounce back.
• Dryness: The moisture barrier weakens with age.

How PDRN & Hyaluronic Acid Work Together

Today, aesthetic procedures have shifted toward biostimulation — harnessing the skin's own biology to regenerate from within. L'Oréal Paris is pioneering this movement with a breakthrough serum inspired by two cutting-edge ingredients*.

*Revitalift Filler Hyaluronic PDRN+ Serum is a cosmetic skincare product for topical use. Results not equal to a procedure.

Hyaluronic Acid: Instant Hydration

HA is the skin's key hydration molecule, capable of holding up to 1,000x its weight in water. Clinical studies have demonstrated that topical HA formulations can help significantly improve skin hydration, reduce the appearance of wrinkle depth, and enhance the feeling of elasticity — particularly when using multi-weight HA that works at different skin surface levels. The Revitalift Filler serum features a multi-weight Hyaluronic Acid complex to help target every skin surface level: Macro HA helps hydrate and smooth the surface, Micro HA helps replump and smooth the appearance of lines, while Micro-Epidermic HA — 50x smaller than macro HA — penetrates deeper within the skin’s surface layer to help replump the appearance of lines and wrinkles.

PDRN: Cellular Biostimulation

PDRN (Polydeoxyribonucleotide) is a DNA-derived ingredient traditionally sourced from salmon sperm. It has become a highly sought-after ingredient in K-beauty and aesthetic clinics, where it is renowned for its ability to help improve overall skin quality and radiance.

L'Oréal Paris' exclusive PDRN+ is a complex of PDRN and PRN produced through bio-fermentation — pure, vegan**, and 3,000x smaller than a pore ensuring optimal absorption into the skin’s surface. It is smaller in both molecular weight and size compared to traditional salmon-derived PDRN.

**Ingredient not of animal origin

Your Anti-Ageing Routine

Building an effective anti-ageing routine doesn't have to be complicated. Here's a simple, science-backed approach including formulas enriched with HA and PDRN+:

1. Cleanse: Start with a gentle cleanser to remove impurities without stripping the moisture barrier.
2. L'Oréal Paris Revitalift Filler Hyaluronic PDRN+ Anti-Wrinkle Plumping Serum: Apply a few drops to clean, slightly damp skin, morning and evening. The fluid lightweight texture delivers an addictive sensory experience — fast-absorbing, non-sticky, non-greasy.
3. Moisturize: Follow with a moisturiser to lock in the serum
4. SPF (AM): Always finish with broad-spectrum sunscreen — the single most important step to prevent premature ageing.

Proven Results

The #1 Anti-Ageing Serum in the World now combines Hyaluronic Acid with our exclusive vegan* PDRN+ for a visible transformation:

Average results – ¹Clinical study with 58 women after 8 weeks, twice daily use. ²Clinical study with 53 women after 6 weeks, twice daily use. Expert visual grading. Individual results will vary.

"Our new Revitalift Filler Hyaluron PDRN + Anti-Wrinkle Plumping Serum relies on the addition of PDRN+ to the existing hyaluronic acid-based formula. This combination supports the serum's established short- and long-term plumping performance and contributes to the visible improvement of lines and wrinkles over time. The addition of PDRN further supports visible benefits on skin glow, elasticity and texture. Evaluated on all skin tones, the formula delivers skin transformation performance on visible signs of skin ageing." — Charlotte Boissard, Skincare Scientific Valorization, L'Oréal Paris

Sources:

• Bravo et al., "Benefits of topical hyaluronic acid for skin quality and signs of skin ageing," Dermatologic Therapy, 2022
• Squadrito et al., "Pharmacological Activity and Clinical Use of PDRN," Frontiers in Pharmacology, 2017
• Akaberi et al., "PDRN in Skincare and Cosmetics: Mechanisms, Therapeutic Applications, and Advancements," J Skin Stem Cell, 2025